A 65-year-old man, weighing 85kg, with moderate renal impairment is prescribed gentamicin for the treatment of a severe bacterial infection.The recommended dosing for gentamicin in patients with moderate renal impairment is an initial loading dose of 5 mg/kg, followed by maintenance doses adjusted based on serum levels. Gentamicin is available as a 40mg/mL solution for injection.After the initial loading dose, the first trough level of gentamicin is measured 24 hours later and is found to be 3mg/L. Based on this result, the dosing interval is adjusted to every 36 hours. To reduce dosing error, each dose is rounded to nearest whole mL.

Given these conditions, how many millilitres (mL) of gentamicin will the patient receive over a 7-day period?

mL
Skip to content